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Aphasia progressiva logopenica

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Conferatur pagina principalis: Aphasia progressiva primaria.

Aphasia progressiva logopenica aphasiarum progressivarum primariarum varietas est[1][2]. Hominibus affectis primum difficultates cogitandi loquendique progressivae sunt, quo reperire verborum progressive tardior erit. Dementiae non symptoma initale est[3]. Morbi causa adhuc incognita est. Tamen observatur accumulatio et amyloidi beta in cerebro, ut morbo Alzheimeriano[4], gravissima, ut demum cellulae nervales pereunt. Damnoso curso hoc atrophia cortex cerebri temporalis posterior sinister, situs concomitatur.

Adhuc sanatione medica caret, inhibitores cholinesterasis, ut morbi Alzheimeriani, praeterea stadio morbi maturo logopaedia[5], commendantur.

Conferatur pagina principalis: Aphasia.

Aphasia amissio facultatis linguam antea quaesitam loquendi comprehendive, detrimento nervorum causa, vel in parte evanescens vel absolute periens dicitur. Aphasia progressiva logopenica vitia phonologica perficit, quo fit, ut sententiarum et perceptio et repetitio deminuuntur[6].

Morbi natura progressiva est, quamquam therapia logopaedica commendatur[7]. Imprimis therapia, quae facultatem nominandi continere potest, aegrotis valorem vivendi addere queat: tractationes ad functiones lexicales semanticasque (verbas quaerendo) recuperandas, ut ad phonologicas (verbas audiendo), orthographicas (legendo scribendoque) spectant.

  1. Henry M. L., Gorno-Tempini M. L. (Dec 2010). "The logopenic variant of primary progressive aphasia". Current opinion in neurology 23 (6): 633-7 
  2. Gorno-Tempini M. L., Hillis A. E., Weintraub S., Kertesz A., Mendez M., Cappa S. F., Ogar J. M., Rohrer J. D., Black S., Boeve B. F., Manes F., Dronkers N. F., Vandenberghe R., Rascovsky K., Patterson K., Miller B. L., Knopman D. S., Hodges J. R., Mesulam M. M., Grossman M. (Mar 2011). "Classification of primary progressive aphasia and its variants". Neurology 76 (11): 1006-14 
  3. Mesulam M. M. (Iun 1982). "Slowly progressive aphasia without generalized dementia". Annals of neurology 11 (6): 592-8 
  4. Santos-Santos M. A., Rabinovici G. D., Iaccarino L., Ayakta N., Tammewar G., Lobach I., Henry M. L., Hubbard I., Mandelli M. L., Spinelli E., Miller Z. A., Pressman P. S., O'Neil J. P., Ghosh P., Lazaris A., Meyer M., Watson C., Yoon S. J., Rosen H. J., Grinberg L., Seeley W. W., Miller B. L., Jagust W. J., Gorno-Tempini M. L. (Mar 2018). "Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia". JAMA neurology 75 (3): 342-52 
  5. Henry M. L., Hubbard H. I., Grasso S. M., Dial H. R., Beeson P. M., Miller B. L., Gorno-Tempini M. L. (Aug 2019). "Treatment for Word Retrieval in Semantic and Logopenic Variants of Primary Progressive Aphasia: Immediate and Long-Term Outcomes". Journal of speech, language, and hearing research 62 (8): 2723-49 
  6. Dial H. R., Gnanateja G. N., Tessmer R. S., Gorno-Tempini M. L., Chandrasekaran B., Henry M. L. (Ian 2021). "Cortical Tracking of the Speech Envelope in Logopenic Variant Primary Progressive Aphasia". Frontiers in human neuroscience: 10.3389/fnhum.2020.597694. eCollection 2020 
  7. Pagnoni I., Gobbi E., Premi E., Borroni B., Binetti G., Cotelli M., Manenti R. (Iul 2021). "Language training for oral and written naming impairment in primary progressive aphasia: a review". Translational neurodegeneration 10 (1): 24  doi:10.1186/s40035-021-00248-z

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