Maprotilinum

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**Maprotilinum**
Natura chemica


Formula chemica	C₂₀H₂₃N
Massa molaris	277.403 g/mol
PubChem	4011
DrugBank	DB00934
Natura pharmacologica
Codex ATC	N06AA21 (WHO)
Tempus semivitae biologicum	27-58 h
Metabolismus	iecore
Excretio	renibus (57%), faecibus (30%)
Ad usum therapeuticum
Applicatio	per os, i.m., i.v.
MedlinePlus	a682158 (Anglice)

Maprotilinum est medicamentum pharmaceuticum cum effectibus antidepressivis et antidepressivum tetracyclicum.

Effectus Maprotilini

Maprotilini effectus antidepressivos, anxiolyticos, sedativos, etiam analgeticos^[1] exercet. Supra partem sympathicam systematis nervosi autonomici stimulat.

Effectus adversi

Effectus adversi, per exemplum, sunt: siccitas oris, exanthema, pruritus, rubor, convulsiones, nausea, vomitus, febris.

Usus Maprotilini

Usus medicus

In psychiatria doses 75-150 mg (in valetudinario usque ad 225 mg) die adhiberi possunt.

Nexus interni

Notae

↑ Banafshe HR, Hajhashemi V, Minaiyan M, Mesdaghinia A, Abed A (2015). "Antinociceptive effects of maprotiline in a rat model of peripheral neuropathic pain: possible involvement of opioid system". Iran J Basic Med Sci 18 (8): 752-7

Nexux externi

Drugs.com: de effectibus Maprotilini adversariis. (Anglice)

[1] Banafshe HR, Hajhashemi V, Minaiyan M, Mesdaghinia A, Abed A (2015). "Antinociceptive effects of maprotiline in a rat model of peripheral neuropathic pain: possible involvement of opioid system". Iran J Basic Med Sci 18 (8): 752-7

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