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Pyruvati kinasis

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Structura trium dimensionum enzymi pyruvati kinasis. In medio moleculae minores phosphoenolpyruvati (rubre) et phosphati depicta

Pyruvati kinasis est enzymum glycolysis termino, quod gregem phosphati ab phosphoenolpyruvato ad ADP transfert, ita pyruvatum et ATP formans[1].

A phosphoenolpyruvato ad pyruvatum

Cofactor: Mg2+

Haec reactio consumit energiam. ΔG° = -31,4 kJ/mol.

Phosphoenolpyruvatum Pyruvati kinasis Pyruvatum
100%
ADP ATP
H+ (Mg2+)
100%

Quattuor isoformae enzymi notae sunt:

  1. Israelsen W. J., Vander Heiden M. G. (Iul 2015). "Pyruvate kinase: Function, regulation and role in cancer". Seminars in cell & developmental biology 43: 43-51 

Nexus interni

Nexus externi

[recensere | fontem recensere]
  • U. S. National Library of Medicine de pyruvati kinasi (Anglice)